The ongoing Prostin supply disruption is beginning to place significant pressure on induction of labour (IOL) services across the UK. As maternity teams work to maintain safe, effective care, many are reviewing and adapting their existing cervical ripening pathways. The current disruption impacts several commonly used prostaglandin options: Prostin® E2 3 mg vaginal tablets (pessary) Prostin® E2 1 mg/2.5 ml gel Prostin® E2 2 mg/2.5 ml gel How Maternity Units Are Responding to