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Prostin Supply Disruption: How UK Maternity Units Are Adapting IOL Pathways

Doctor consults woman holding her belly in an exam room. Doctor holds a tablet, both appear focused. Background shows medical equipment.


The ongoing Prostin supply disruption is beginning to place significant pressure on induction of labour (IOL) services across the UK. As maternity teams work to maintain safe, effective care, many are reviewing and adapting their existing cervical ripening pathways.


The current disruption impacts several commonly used prostaglandin options:

  • Prostin® E2 3 mg vaginal tablets (pessary)

  • Prostin® E2 1 mg/2.5 ml gel

  • Prostin® E2 2 mg/2.5 ml gel



How Maternity Units Are Responding to the Prostin Shortage


Across the UK, maternity teams are demonstrating resilience and adaptability. A growing number of units are:

  • Increasing use of mechanical methods of cervical ripening

  • Reviewing clinical pathways to reduce reliance on prostaglandins

  • Expanding outpatient induction options where appropriate


One solution seeing increased adoption is DILAPAN-S, a mechanical cervical ripening method.


Expanding Use of DILAPAN-S


For teams already using DILAPAN-S, scaling up has proven to be straightforward to implement, effective in managing supply shortage, and aligned with existing clinical workflows


For units new to DILAPAN-S, the disruption has created an opportunity to:

  • Broaden patient choice

  • Introduce non-pharmacological induction options

  • Build more resilient IOL pathways


dilipan on a tray

Why Consider DILAPAN-S?


DILAPAN-S offers several clinical and operational benefits that are particularly relevant during supply challenges:


  • Predictable cervical ripening with gradual, controlled dilation

  • Drug-free option, suitable for patients who cannot or prefer not to use pharmacological methods

  • High maternal satisfaction reported in clinical use

  • Supports mobility and outpatient induction pathways

  • Shown to optimise staff time and resources




Support for Maternity Teams


To help services navigate the current disruption, a range of support is available for both new and existing users:


Implementation Support

  • Assistance with standard operating procedure (SOP) development

  • Guidance on integrating DILAPAN-S into existing pathways

Get implementation support here.


Training & Education

  • In-person and virtual training for multidisciplinary teams

  • Access to concise training videos for flexible learning - Watch here.

  • Live webinars covering practical implementation and shared experiences - Register here.


Clinical & Procurement Guidance

  • Access to clinical evidence and best practice guidance

  • Support with procurement processes and onboarding



Strengthening IOL Pathways for the Future


While the Prostin supply disruption presents immediate challenges, it also offers an opportunity for services to:

  • Reassess induction pathways

  • Improve service flexibility and resilience

  • Enhance patient-centred care through expanded choice



Get Personalised Support


Every maternity unit is managing this situation differently. Tailored support can help ensure a smooth transition and maintain high standards of care.


If your team is reviewing its IOL pathway, now is a good time to explore how alternative approaches like DILAPAN-S could fit within your service.



Gynaecology medical devices UK

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Maternity & Neonatal Medical Devices Supplier In The UK

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Registered as Advanced Global Health Ltd in England. Registration number 07181386

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