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New Evidence: The WID-easy Test Can Reduce NHS Costs

The WIDeasy test

Snowsill et al.; Cost-minimisation analysis of the WID-qEC epigenetic biomarker compared to transvaginal ultrasound for triaging abnormal uterine bleeding. Value in Health, 2026


A newly peer-reviewed cost-minimisation analysis published in Value in Health demonstrates that WID-easy offers a compelling economic and clinical alternative to transvaginal ultrasound (TVUS) as the first-line triage test for patients presenting with abnormal uterine bleeding (AUB) referred to the Urgent Suspected Cancer pathway.



Key Findings of the Cost Analysis


  • TVUS has a low specificity resulting in many unnecessary procedures, which are often invasive, painful and costly.

  • Utilising the data from the prospective, observational EPI-SURE study, a cost minimisation analysis was undertaken.

  • A decision tree model was created to simulate the costs associated with the current standard of care versus use of the WID-easy test from initial triage to definitive evaluation as part of the short term diagnostic pathway (Urgent Suspected Cancer pathway).

  • The model evaluated cost-savings associated with replacing TVUS with the WID-easy test and the subsequent reductions in unnecessary histology (Pipelle, OP hysteroscopy, GA hysteroscopy).

  • At a list price of £150.00, utilising the WID-easy test (UKCA version) would create a saving of £181.00 per patient that enters the pathway.

  • The mean breakeven price calculation indicated that if the test was sold at £302, the breakeven point would be met.


There is a >99% probability that using the WID-easy test would result in cost savings for the Urgent Suspected Cancer Pathway.


Hospital corridor scene: Nurse in blue scrubs pushes a gurney. Two medical staff converse. Patient in a wheelchair with a doctor nearby.

With urgent suspected gynaecological cancer referrals more than doubling over the past decade, NHS services are under growing pressure.


Evidence continues indicate that the WID-easy test may offer a range of benefits, including:

  • Reducing unnecessary hysteroscopies and biopsies

  • Minimising painful invasive procedures for patients

  • Increasing ultrasound capacity for other populations

  • Reducing waiting list pressures in overstretched gynaecology pathways




Clinical Value Beyond Cost of the WID-easy Test


In peer-reviewed research, WID-easy has demonstrated:

  • Equivalent sensitivity to TVUS for endometrial cancer detection 2,3

  • Higher specificity than TVUS 2,3

  • Much lower failure rates than ultrasound in routine triage settings 2,3


WID-easy offers fewer false positives, fewer inconclusive results, resulting in the potential for a more efficient pathway for triaging risk of endometrial cancer.


A doctor in a white coat smiles, holding hands with a patient in a striped sweater. They sit in a bright medical office, fostering a warm mood.


References

  1. Snowsill et al., 2026

  2. Evans et al.  2023. EPI-SURE

  3. Ken-Amoah et al., IJC, 2024


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